CannaTrials adheres to evidence-based medicine – making statements based on medical evidence.

This page is excerpted and quoted from the National Academies of Science, Engineering, and Medicine.    A Committee of over 40 experts, researchers, and reviewers in The Health and Medicine Division published a 486 page report in 2017 entitled “The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research.
If you would like to access the entire report you may do so by clicking this link.

Medical Marijuana and Later Outcomes

“The committee did not identify a good- or fair-quality systematic review that reported on the association between cannabis exposure and later outcomes for the child.

The literature reviewed above does not support an effect of cannabis exposure on overall cognitive function, although some variation in subscale scores has been seen. Only one study has examined overall child behavior, and it found that the results did not persist. More consistency is seen for adolescent outcomes, with increased delinquency, greater cigarette and cannabis use, and some suggestion of increased mental health symptoms. For the later outcomes, attributing the outcomes to prenatal exposures is particularly difficult. While the studies attempted to control for the child’s environment using standard measures of socioeconomic status as well as a direct assessment of the home environment, these approaches may be insufficient to detect potentially subtle differences in the family and neighborhood environments of women who smoke cannabis during pregnancy and those who do not. For example, the association of prenatal cannabis exposure and adolescent substance use may reflect family/neighborhood influences and may not be a direct effect of the prenatal exposure. Likewise, maternal distress/depression during pregnancy, which is likely to continue postpartum, may influence both the use of cannabis and child developmental outcomes. In addition, these studies did not address heritable or epigenetic vulnerability.

CONCLUSION 10-4 There is insufficient evidence to support or refute a statistical association between maternal cannabis smoking and later outcomes in the offspring (e.g., sudden infant death syndrome, cognition/academic achievement, and later substance use. [1]

[1] The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research | The National Academies Press. 2017. Pages 254-260Download the complete 486 page report.

**Important Note:  On many of the health conditions studied by NAS, there was no conclusive evidence of cannabis effectiveness from the study results they reviewed.  The authors included a long section on “research gaps.

It is the Vision and Mission of CannaTrials to fill in some of these research gaps with cannabis clinical trials using specific medical marijuana formulations and testing them in a research protocol with local patients, physicians, processors and dispensaries.  If you are interested in participating in a clinical trial, and helping improve scientific knowledge about health effects of cannabis, please click one of the buttons below on this page.

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